A prospective multicenter observational study assessing risk factors for acute blood transfusion reactions in dogs.
This large prospective multicenter study tracked 1542 allogenic transfusions (predominantly pRBCs, whole blood and plasma products, but also including platelet and albumin products) to 858 dogs in the US, UK and Australia.
Some Takehomes:
- Transfusion reactions occurred in 8.9% of pRBC transfusions, with the most common reactions being febrile nonhemolytic transfusion reactions (in 4%), acute hemolytic transfusion reactions (in 2.3%) and allergic reactions (mainly cutaneous and vomiting, in 2.2%).
- No anaphylactic reactions were documented.
- The age of the pRBC unit was positively associated with the odds of developing a transfusion reaction.
- Leukoreduction of pRBCs was not associated with reduced odds of a transfusion reaction.
- The most frequent justification for use of plasma was colloidal and volume support.
Read the Full Report Here
A prospective multicenter observational study assessing incidence and risk factors for acute blood transfusion reactions in dogs (Journal of Internal Veterinary Medicine, Open Access)
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