Your monthly update and overview of recently released veterinary studies.
Welcome to our monthly VetLit Clinical Publication update, where Dr Simon Cook, founder of VetLit.org, provides an overview and update on recently released studies from a wide range of veterinary publications.
Study: Prevalence, Associated Disease Mechanisms, and Outcome of Dogs and Cats With Low Blood Sodium-to-Potassium Ratio (Journal of Veterinary Emergency & Critical Care)
About the Study:
Yes, we talk about the Na:K ratio a lot, and yes it ‘works’ but that’s in part because we use it in populations of dogs where the pre-test probability of having hypoadrenocorticism is high. (We might not even consider the ratio in a dog that clearly has a non-hypoA cause of its presentation).
Look at it another way round – how common is a Na:K of <27 and what are the diseases most frequently associated with an Na:K of <27? Answers (in this sample population of dogs): Prevalence = 6.7%; and not hypoA. Although, hypoA did generate the lowest median Na:K ratio (median of 22) and lowest median sodium concentrations (median 133mmol/L) compared to other disease states.
The most common causes were urinary (renal) in origin, or postulated to be related to states of decreased effective circulating volume.
Read the full study HERE
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