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Welcome to our monthly VetLit Clinical Publication update, where Dr Simon Cook, founder of VetLit.org, provides an overview and update on recently released studies from a wide range of veterinary publications.
In this study 153 cases of uncomplicated, surgically managed pyometra were randomised to receive 5 days of TMPS or placebo post-operatively, irrespective of whether bacteriuria was documented at the time of surgery. (All dogs received a single dose of IV TMPS pre-operatively). Frequency of urinary tract infection or surgical site infection were then assessed at 12 and 30 days. Neither were higher in the placebo group. Of the 22 dogs with bacteriuria documented at surgery that received placebo, none displayed clinical evidence of a UTI by 12 days and 14 were cultured positive again at day 12. Clinical recoveries were similar across both groups (see table 5).
I don’t doubt that these practices could likely be pushed further and very much look forward to this over time, but a due diligence reminder that these were stable dogs. Dogs that were pyrexic and leukopenic or hypoglycaemic were excluded, as were those considered ASA grade 4 or 5.
Simon graduated from the University of Bristol in 2011 with degrees in veterinary science and veterinary pathogenesis. After a rotating internship at the Royal Veterinary College and two years in a busy 24 hour small animal hospital, he completed a residency in emergency and critical care at the Royal Veterinary College. He is currently a senior lecturer in emergency and critical care at the Royal Veterinary College, London. Clinical and research interests combined include immunomodulation, cardiovascular monitoring, patient side ultrasonography and aspiration pneumonia. VetLit.org is his passion project, making literature more accessible to anyone and everyone.
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